Endocrine Abstracts

Background: Thyroid dysgenesis (TD) represents a heterogeneous group of conditions and accounts for 85% of cases of congenital hypothyroidism (CH). This can be due to abnormal gland organogenesis which results in thyroid agenesis (35–40% of the cases), thyroid hypoplasia (5%) and thyroid ectopy (30–45%).Causes of CH can be classified into: one. dyshormonogenesis usually associated with goiter, caused by mutations in the genes coding for the pro...